The PRBB animal facility is one of the most complex and automated in Europe and has capacity for 70,000 mice under SPF conditions as well as 50,000 zebrafish.
In an area of over 4,500 m2, the PRBB animal house comprises six separate units, which are connected and administered under a single manager:
- Area for aquatic animals (Xenopus frogs and zebrafish)
- Barrier zone: specific pathogen-free (SPF), with modern ventilated microisolators. This also has three support laboratories.
- Transgenesis area: large laboratories (250 m2) to apply both traditional and the most innovative techniques, able to generate genetically modified mice.
- Experimental area: equipped with laboratories for in vivo imaging, rooms for behavioural studies, surgery rooms and an irradiator.
- Quarantine area: with its own locker room access, rederivation laboratory for embryo transfer, laundry and sterilization, and four different rooms with modern microisolators.
- Conventional animal house: located in the adjacent building at no. 80 Doctor Aiguader, and connected to the PRBB building via an underground tunnel. It has an area of 1,300 m2 for neuropharmacology and immunology studies.
As of June 2010, the programme of care and use of laboratory animals has the full accreditation from the Association for Assessment and Accreditation of Laboratory Animal Care (AAALAC). This is the highest international certification in the field and is a recognition of the quality of the running of the centre which results in better practice and improved research results.
The PRBB has an Ethical Committee for Animal Research (CEEA-PRBB) which evaluates project procedures using experimental animals, taking into account the appropriateness of the procedure in relation to the objectives of the study, the possibility of reaching valid conclusions with the fewest animals, the effect on the animals not being disproportionate to the potential benefits of the research, and, in short, the avoidance of unnecessary suffering, as well as considering the possibility of alternative methods to the use of animals.
The capacities of the PRBB animal facility meets the needs of the critical mass of researchers at the park, but also provides services to external public and private entities. Please contact the director of the animal facility (see above) so that feasability and requirements (ethical committees, biosafety, etc.) can be checked.