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  • “Cells function as a remarkably synchronized orchestra of finely tuned molecular interactions, and establishing this molecular network has become a major goal of molecular biology,” states the team of Dr. Alfonso Valencia, of the Spanish National Cancer Research Center (CNIO).

  • The pharmaceutical industry is “taking too long, spending too much and producing far too little.” This harsh criticism came from someone with intimate knowledge of the industry, John Lechleiter, CEO of Eli Lilly until his retirement at the end of 2016. The analysis was taken up in The Future of Drug Discovery, a publication in which the former executive spared no irony in his assessment of the problems and challenges facing biomedical research.

  • The pharmaceutical industry is “taking too long, spending too much and producing far too little.” This harsh criticism came from someone with intimate knowledge of the industry, John Lechleiter, CEO of Eli Lilly until his retirement at the end of 2016. The analysis was taken up in The Future of Drug Discovery, a publication in which the former executive spared no irony in his assessment of the problems and challenges facing biomedical research.

  • La Cartuja Island, nestled between two arms of the Guadalquivir River in central Seville’s Triana district, is home to some of Spain’s leading research institutes. Denizens like the Doñana Biological Station, the National Center for Accelerators, the Institute for Microelectronics and the Andalusian Molecular Biology and Regenerative Medicine Center all call the Cartuja93 Technological Park home.

  • In October 2011, an international consortium of scientists launched the project BLUEPRINT, an initiative backed by thirty million euros in funding from the European Commission. The goal was to determine how genes are activated or repressed; in other words, trace the epigenetic blueprint of blood cells. The secrets of the mechanisms that activate and repress gene expression are fundamental to understanding the appearance of certain pathologies related with blood cells, such as different types of cancer, diabetes or autoimmune diseases.

  • The Center for Research in Agricultural Genomics (CRAG) is a forerunning institute in the research of the molecular bases of genetic characters of interest in plants and farm animals. This independent organization was founded as a consortium made up by the Autonomous University of Barcelona (UAB), the Council of Scientific Research (CSIC), the University of Barcelona (UB) and the Institute of Agrifood Research and Technology (IRTA).

  • Nanoscience and nanotechnology are no longer unknown disciplines in the pharmaceutical and cosmetic industries. The usage of structures and nanoparticles under 100 nm is becoming more commonplace. One example are liposomes, inside which active substances can be stored, or that can be used to transport and free any substance of interest in the body or on the skin.

  • Every day thousands of scientists around the world sequence and analyze millions of genetic data. In clinical practice, the information they compile is used to determine possible somatic mutations that could play a role in the diagnosis, prognosis and treatment of diseases. The DNA sequencing of a tumor can be done in three different ways: analyzing the entire genome, reading only the genome’s coding portion (exome) or through panels.

  • Cancer is a leading cause of morbidity and mortality around the world. According to data from the World Health Organization, 14 million new cases were detected in 2012 and more than eight million individuals died from a malignant tumor. Today, the main challenge faced by oncology is the therapeutic approach to metastasis, a problem known for decades, which is still the top cause of mortality within this wide range of diseases.

  • Wilhelm Kühne, known for coining the term “enzyme”, was the biochemist who extracted something he called “visual purple” from a bovine retina. In the midst of the 19th century, the scientist proposed that this molecule was a key part of the vision process. He wasn’t wrong. This light-capturing “antenna” is the main protein component of the membrane surrounding the outer segment disc of the retina’s rod cells.

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