The IRB Barcelona Drosophila Injection Service generates transgenic flies for researchers within IRB Barcelona and their collaborators. The facility was set up in January 2006 and is staffed by Ainoa Olza. The transgenic fly plays a crucial role in basic and applied biomedical research. The study of normal and abnormal gene expression, of regulatory elements and of gene mutations relevant for human disease are examples of applications of genetically modified animal models in experimental research.