In 2010, Sonia Vallabh was working as an attorney in a US law firm when her mother died due to a rare disease known as fatal familial insomnia. The pathology is a prion disease that has been observed in some 100 patients around the world. Forty of them live in Spain, almost half of them in the Basque Country.
Cell sorting is fast becoming an essential step on the path to deeper understanding and new discoveries in the life sciences. This technology is expanding to a wide range of applications such as immunology, stem cell research, genomics, bioprocessing and cancer biology. A readily available on-site sorter that provides consistent, reliable results could benefit researchers in many fields of investigation.
Nanoimprint lithography (NIL), or simply imprint lithography, is one of the pioneering techniques in nanotechnology, used to fabricate nanometer-scale structures. One of the leading experts in this discipline is Dr. Nikolaos Kechagias. He directs the Nanoimprint Lithography platform of the Catalan Institute of Nanoscience and Nanotechnology (ICN2).
The presence of epithelial cells in the bloodstream of a woman with metastatic breast cancer was discovered by T.R. Ashworth more than 150 years ago. His discovery would make it possible to determine, decades later, the existence of circulating tumor cells to monitor the evolution and progression of cancer.
No one can question the advancements represented by DNA sequencing. The contribution made by technological cores specialized in genomics has made possible the first molecular consensus on colorectal cancer. The arrival of a new technique, especially if it is as innovative and revolutionary as this one, always implies the abandonment of other technologies.
Colorectal cancer is one of the most common types of cancer. While more predominant in older patients, with an average age of presentation of 70-71 years, it is still considered the cancer with the second-highest incidence in western countries. In male patients, only lung cancer is more prevalent, while in women, the most common is breast cancer.
Seven years ago, the launch of the International Cancer Genome Consortium (ICGC) ushered in a new era in the understanding of cancer, with the goal of improving clinical diagnosis and treatment of patients.
After tragically losing his parents to cancer, the British scientist decided to dedicate his life to his work. Shortly after completing his doctoral thesis, Sanger began to take an interest in protein sequencing, and his research earned him his first Nobel Prize in Chemistry in 1958, after he deciphered the complete sequence of insulin.