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bioinformatics

A computational model to determine the progression of colorectal cancer

Colorectal cancer is one of the most common types of cancer. While more predominant in older patients, with an average age of presentation of 70-71 years, it is still considered the cancer with the second-highest incidence in western countries. In male patients, only lung cancer is more prevalent, while in women, the most common is breast cancer.

Ivo Gut (CNAG): “Sequencing has evolved more than computers in the last ten years”

Cambridge is an emblematic city in the history of science. Nestling among faculties and laboratories lies the Biochemistry Department, where illustrious researchers of the ilk of Hans Kornberg and César Milstein once worked. It was also where a young Fred Sanger completed his PhD in 1943.

After tragically losing his parents to cancer, the British scientist decided to dedicate his life to his work. Shortly after completing his doctoral thesis, Sanger began to take an interest in protein sequencing, and his research earned him his first Nobel Prize in Chemistry in 1958, after he deciphered the complete sequence of insulin.